I usually ignore it. I try to get rid of the bugs that give shrouded first, then all other synapse. Then I play the mission. Last game I played against nids: 1000pts, I flyrant, I ignored it till turn four. By then my opponent had no other synapse and no shrouded either. Grantwd , the flyrand did make a mess of a few of my boats, but I still had enough to flat out to the objectives I needed. It forced the flyrant to have a limited fly range or he would break synape from the rest of his army